OFFICE LOCATIONS

Childrens Hospital of Buffalo
219 Bryant Street
Buffalo, NY 14222

Phone: 878-7177
Fax: 888-3833
Email: lburkman@acsu.buffalo.edu
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EDUCATION

1983 Reproductive Physiology, Reproductive Physiology
University of California, Davis
1973 Endocrinology, Endocrinology
University of California, Davis.
1971 Zoology, Zoology
University of California, Santa Barbara


PUBLICATIONS

Burkman LJ, Bodziak ML, Mroz RL, Gurunatha R, Palaszewski D, Kiouranakis N, Beardsley S; Changes in human sperm function and semen quality due to cholinergic agonists or tobacco use; J Andrology; 2008;
Burkman LJ, Gurunatha R, Shelton JA; Clarification of CASA assessment of hyperactivated motility; J Andrology; 2008;
Burkman LJ, Kiouranakis n, Telesz B, Rafferty R, Rizvi A, Joulak F.; Impact of tobacco use on human sperm function: hyperactivation, semen quality and acrosomes; J Andrology; 2008;
Burkman LJ, Gurunatha R, Gonzalez F, Sacrione EJ, Shelton JA.; Sperm hyperactivation as a reliable predictor of pregnancy/fertilizing potential; Human Reproduction; 2008;
Burkman LJ, Schuel H; Endocannabinoids in Fertilization, Pregnancy and Development; ; 2006;
Burkman LJ, Tambar S, makriyannis A, Bodziak M, Mroz R, Telesz B, Kiouranakis N; Fertility loss in the sperm of tobacco smokers may be reversed after washing with a cannabinoid agonist.; Fertil Steril; 2006; 86(2); S285
Burkman LJ, Crickard K, Gonzalez F, Krande VC, Mbizvo MT, Alexander NJ, Sarcione EJ, Shelton JA; Sperm hyper activation as a reliable predictor of pregnancy/fertilizing potential: maximizing the semen analysis; ; 2006;
Schuel H, Burkman LJ; A tale of two cells: endocannabinoid-signaling regulates functions of neurons and sperm.; Biol Reprod; 2005 Dec; 73(6); 1078-1086
Burkman LJ, Schuel H; A Tale of Two Cells: Retrograde Endocannabinoid Signaling in Neurons and Sperm; Program Supplement 15th Annual Symposium of the Cannabinoids; 2005;
Burkman LJ, Schuel H, Makriyannis A, Bodziak ML, Mroz R, Guranatha R; In human spermatozoa, a cannabinoid agonist can inhibit the effects of nicotine on hyperactivation (HA): Potent interaction of two regulatory systems; Program Supplement 15th Annual Symposium of the Cannabinoids, International Cannabinoid Research Society; 2005;
Burkman LJ, Mroz R, Bodziak ML, Tambar S, Beardsley S, Telez B; The sperm from most chronic tobacco smokers exhibit a significant decline in the ability to bind to the human egg.; Fertil Steril; 2005; 84(1); S13-S14
Burkman LJ, Schuel H; The neuron is a sperm cell without a tail: a perspective on endocannabinoid signaling; Program Supplement; 2004;
Burkman LJ, Sugiura T, Makriyannis A, Schuel H; Anandamide and 2-Arachidonoylglycerol are present in rabbit reproductive organs and can modulate motility in human sperm.; Program Supplement 13th Annual meeting of the International Cannabinoid Research Society; 2003;
Burkman LJ, Bodziak ML, Schuel H, Palaszewski D, Gurunatha R, Mroz R, Borelli C; Marijuana (MJ) impacts sperm function both in vivo and in vitro: semen analyses from men smoking marijuana; Fertil Steril; 2003; 80(3); S231
Schuel H, Burkman LJ, Lippes J, Crickard K, Forester E, Piomelli D, Giuffrida A; N-Acylethanolamines in human reproductive fluids.; Chem Phys Lipids; 2002 Dec; 121(1-2); 211-227
Schuel H, Burkman LJ, Lippes J, Crickard K, Mahony MC, Giuffrida A, Picone RP, Makriyannis A; Evidence that anandamide-signaling regulates human sperm functions required for fertilization.; Mol Reprod Dev; 2002 Nov; 63(3); 376-387
Burkman LJ, Bodziak M, Gurunatha R, Palaszewski D, Mroz R; Nicotine and the fertilization story: smoking versus endogenous function.; Fertil Steril; 2002; 78(3S); S168
Burkman LJ, Schuel H, Lippes J, Makriyannis A, Giuffrida A; Endocannanbinoids: discovery of a unique signaling system for regulating sperm function and fertilization.; Progrm Supplement American Society for Reproductive Medicine; 2001;
Burkman LJ, Guiffrida A, Piomelli D, Lippes J; N-Acylethanolamides in human reproductive fluids; Program Supplement; 2001;
Burkman LJ; N-acylethanolamides in human reproductive secretions: implications for marijuana abuse; Program Supplement NIDA symposia on Cannabinoids; 2001;
Burkman LJ, Schuel H, Lippes J, Picone R, Makriyannis A, Mahony M, Giuffrida A, Piomelli D; An endocannabinoid-signal system regulates human sperm; Mol Biol Cell; 2000; 11; 404a
Burkman LJ, Schuel H, Chang MC, Zimmerman A, Hill A, Picone RP, Makriyannis A.; Cannabinoid receptors in sperm; ; 1999;
Burkman LJ, Lethin PE, Frazier D, Crickard Kent, Sullivan M, Gonzalez F; Pregnancy failure is more accurately predicted by split ejaculate semen evaluation; Program Supplement Annual Meeting of the American Society of Reproductive Medicine; 1999;
Burkman LJ, Schuel H, Picone LJ, Makriyannis A; Functional cannabinoid receptors in human sperm; Program Supplement Annual Meeting of the American Society for Cell Biology; 1998;
Burkman LJ; Instability of sperm nuclei and acrosomes in higher among infertile men.; Journal of Urology; 1998; 159; 268
Burkman LJ, Schuel H, Picone RP, Bo T, Makriyannis A; Marijuana-like (cannabinoid) receptors on human and sea urchin sperm and their probable role as modulators of fertilization; Program Supplement 8th International Symposium on Spermatology; 1998;
Burkman LJ, Schuel H, Picone RP, Bo T, Makriyannis A; Marijuana-like (cannabinoid) receptors on human sperm and their probable role as endogenous modulators of fertilization events: acrosome reaction hyper activation and zone binding.; Program Supplement 54th Annual Meeting of the American Society for Reproductive Medicine; 1998;
Burkman LJ; Quick, reliable and inexpensive toxicity assay based on changes in human sperm hyper activated (AH) swimming percent motility.; Program Supplement Hazardous Substances and male Reproductive Health; 1998;
Burkman LJ, Schuel H, Picone RJ, Bo T and Makriyannis A; Cannabinoid receptors in human sperm; Mol. Biol Cell; 1997; 8; 325a
Burkman LJ; Cannabinoids can alter human sperm acrosome reactions (AR); Program Supplement 53rd Annual Meeting of the Am Soc for Reproductive Medicine; 1997;
Burkman LJ, Schuel H, Hill WA, Picone RP, Makriyannis A; Evidence for cannabinoid receptors in human sperm; Program Supplement Symposium on Cannabinoids; 1997;
Burkman LJ; New assays for evaluating human sperm function; ; 1996;
Burkman LJ, Bodziak ML, Crickard K, Gonzalez F, Bhakoo H, Sarcione EJ, Shelton J; Sperm hyperactivation (HA) as a critical part of the semen analysis.; Program Supplement 52nd Annual Meeting of the Am Soc for Reproductive Medicine; 1996;
Burkman LJ; Motility of human spermatozoa during capacitation; ; 1995;
Oehninger S, Sueldo C, Lanzendorf S, Mahony M, Burkman LJ, Alexander NJ, Hodgen GD; A sequential analysis of the effect of progesterone on specific sperm functions crucial to fertilization in vitro in infertile patients.; Hum Reprod; 1994 Jul; 9(7); 1322-1327
Burkman LJ; Human sperm hyperactivation and CASA analysis as a rapid QC/toxicity assay.; Program Supplement 50th Annual Meeting of the American Fertility Society; 1994;
Shibahara H, Burkman LJ, Isojima S, Alexander NJ; Effects of sperm-immobilizing antibodies on sperm-zona pellucida tight binding.; Fertil Steril; 1993 Sep; 60(3); 533-539
Sueldo CE, Oehninger S, Subias E, Mahony M, Alexander NJ, Burkman LJ, Acosta AA; Effect of progesterone on human zona pellucida sperm binding and oocyte penetrating capacity.; Fertil Steril; 1993 Jul; 60(1); 137-140
Burkman LJ, Kiessling AA, Rogers BJ, Epstein DA; Comparison of three quality control (WC) assays: human sperm, mouse,hamster egg penetration.; Program Supplement International Congress on IVF/ET Japan; 1993;
Burkman LJ, Samrock RL; Human sperm hyperactivation assay: repeatable values within individual men.; Program supplement Internat Congress on IVF/ET, Japan; 1993;
Burkman LJ, Oehninger S, Sueldo C, Mahony M, Alexander NJ; Effect of progesterone on human sperm functions: hyper activated motility, acrosome reaction, zona pellucida binding and oocyte penetration.; Program Supplement 48th Annual Meeting of the American Fertility Society; 1992;
Burkman LJ, Coddington CC, Oehninger SC, Franken DR, Kruger TF, Hodgen GD; Hemizona Index (HZI) demonstrates excellent predictability when evaluating sperm fertilizing capacity in in vitro fertilization (IVF) patients; Program Supplement Annual Meeting of the American Society of Andrology; 1992;
Burkman LJ, Samrock RL; Sperm hyperactivation (HA) assay; values are repeatable within individual men; Program Supplement 48th Annual Meeting of teh American Fertility Society; 1992;
Franken DR, Coddington CC, Burkman LJ, Oosthuizen WT, Oehninger SC, Kruger TF, Hodgen GD; Defining the valid hemizona assay: accounting for binding variability within zonae pellucidae and within semen samples from fertile males.; Fertil Steril; 1991 Dec; 56(6); 1156-1161
Burkman LJ; Discrimination between nonhyperactivated and classical hyperactivated motility patterns in human spermatozoa using computerized analysis.; Fertil Steril; 1991 Feb; 55(2); 363-371
Shibahara H, Shigeta M, Koyama K, Burkman LJ, Alexander NJ, Isojima S; Inhibition of sperm-zona pellucida tight binding by sperm immobilizing antibodies as assessed by the hemizona assay (HZA).; Nippon Sanka Fujinka Gakkai Zasshi; 1991 Feb; 43(2); 237-238
Burkman LJ, Epstein DA, Rogers BJ, Kuligowski S; A modified yolk buffer for human sperm refrigeration supports enhanced motility; Program Supplement 7th World Congress on In Vitro Fertilization and Assisted Procreations; 1991;
Burkman LJ, Rogers BJ, Kiessling AA, Epstein DA; Comparing three reproductive assays for their quality control (QC) potential; Program Supplement 47th Annual Meeting of the American Fertility; 1991;
Burkman LJ; Cryopreservation of hyman sperm is detrimental to hyper activated motility potential; Program Supplement Annual meeting of the American Society of Andrology; 1991;
Burkman LJ, Franken DR, Oosthuizen WR, Cooper S, Kruger TF, Coddington CC, Hodgen GD; Electron microscopic evidence on the acrosomal status of bound sperm and their penetration into human hemizonae pellucida after storage in a buffered salt solution; Andrologia; 1991; 23; 205-208
Coddington CC, Franken DR, Burkman LJ, Oosthuizen WT, Kruger T, Hodgen GD; Functional aspects of human sperm binding to the zona pellucida using the hemizona assay.; J Androl; 1991 Jan; 12(1); 1-8
Burkman LJ; Inhibition of sperm-zona pellucida tight binding by sperm immobilizing antibodies as assessed by the hemizona assay (HZA).; Acta Obstetrica Et Gynaecologica Japonica; 1991; 43(2); 237-238
Burkman LJ; Physiological aspects of sperm hyper activated motility (HA) and implications for infertility; Program Supplement 2nd International Congress on Therapy in Andrology; 1991;
Burkman LJ; The Hyperactivation Assay (HA): A diagnostic tool and a quality control test.; Program Supplement 2nd international Congress on Therapy in Andrology; 1991;
Burkman LJ, Oehninger S, Franken DR, Kruger T, Coddington CC, Hodgen GD; Validation of the hemizona assay (HZA): Influence of oocyte storage method and nuclear maturational stage on sperm binding ability; Program Supplement 7th World Congress on In Vitro Fertilization and Assisted Procreations; 1991;
Mbizvo MT, Burkman LJ, Alexander NJ; Human follicular fluid stimulates hyperactivated motility in human sperm.; Fertil Steril; 1990 Oct; 54(4); 708-712
Burkman LJ, Coddington CC, Oehninger S, Hodgen GD; Accommodating low sperm concentration in the hemizona sperm-binding assay (HZA); Program Supplement Annual Meeting of the Society for Gynecologic Investigation; 1990;
Burkman LJ, Oehninger S, Alexander NJ, Franken DR, Coddington CC, Kruger TF, Acosta AA, Hodgen GD; Antifertilization Assays; ; 1990;
Burkman LJ, yanagida K, Hoshi K, Sato A; Automated semen analysis shows an increase in sperm concentration and motility with time in Makler chambers having excess sample volume; Human Reprod; 1990; 5(2); 193-196
Burkman LJ; Computer-automated versus visual analysis of human sperm hyperactivation (HA); Program Supplement Annual Meeting of the American Fertility Society; 1990;
Burkman LJ, Mbizvo MT, Alexander NJ; Follicular fluid stimulates human sperm hyperactivation; Program Supplement J Andrology; 1990;
Burkman LJ, Mbizvo MT, Alexander NJ; Human follicular fluid stimulates hyper activated motility in human sperm; Fertil Steril; 1990; 54; 708-712
Burkman LJ; Hyperactivated motility of human spermatozoa during in vitro capacitation.; ; 1990;
Burkman LJ, Karande VC, Mbizvo MT, Veeck L, Alexander NJ; Hyperactivation (HA) of human sperm is a prognostic indicator of fertilization during IVF; Program Supplement J Andrology; 1990;
Burkman LJ; Mouse pre-embryo survival after biopsy and nucleation; Program Supplement Annual Meeting of the Society for Gynecologic Investigation; 1990;
Burkman LJ; The Hemizona Assay (HZA): Assessment of fertilizing potential by means of human sperm binding to the human zona pellucida; ; 1990;
Oehninger S, Coddington CC, Scott R, Franken DA, Burkman LJ, Acosta AA, Hodgen GD; Hemizona assay: assessment of sperm dysfunction and prediction of in vitro fertilization outcome.; Fertil Steril; 1989 Apr; 51(4); 665-670
Franken DR, Oehninger S, Burkman LJ, Coddington CC, Kruger TF, Rosenwaks Z, Acosta AA, Hodgen GD; The hemizona assay (HZA): a predictor of human sperm fertilizing potential in in vitro fertilization (IVF) treatment.; J In Vitro Fert Embryo Transf; 1989 Feb; 6(1); 44-50
Burkman LJ; Comparison of tight sperm binding to the zona pellucida in the Hemizona Assay (HAZ) utilizing fresh versus frozen sperm from the same male; Program Supplement Annual Meeting of the American Society of Andrology; 1989;
Burkman LJ; Criteria for identification of human hyper activated (HA) sperm: an introduction to visual and computer-assisted methods; Fertilization in Mammals; 1989;
Franken DR, Burkman LJ, Oehninger SC, Coddington CC, Veeck LL, Kruger TF, Rosenwaks Z, Hodgen GD; Hemizona assay using salt-stored human oocytes: evaluation of zona pellucida capacity for binding human spermatozoa.; Gamete Res; 1989 Jan; 22(1); 15-26
Burkman LJ, Coddington CC, Oosthuizen WT, Franken DR, Hodgen GD, Kruger TF; Maintenance of pH is essential in oocyte storage media for the hemizona assay (HZA); Program supplement Annual Meeting of the American Fertility Society; 1989;
Burkman LJ; Movement characteristics of four classes of human sperm hyperactivation: criteria for computerized identification.; Program Supplement Annual Meeting of the American Fertility Society; 1989;
Burkman LJ, Franken D, Coddington C, Osthuizen T, Kruger T, Hodgen GD; Optimal binding kinetics for fertile and infertile spermatozoa are similar when evaluated with hemizona assay (HZA); Program Supplement Annual Meeting of the Society for Gynecologic Investigation; 1989;
Burkman LJ, Franken DR, Hodgen GD, Coddington CC, Oehninger S; The Hemizona Assay (HZA) to assess the fertilizing potential in human spermatozoa.; ; 1989;
Burkman LJ, Franken DR, Oehninger SC, Coddington CC, Veeck LL, Kruger TJ, Rosenwaks Z, Hodgen GD; The Hemizona Assay using salt stored human oocytes: evaluation of zona pellucida capacity for binding human spermatozoa; Gamete Res; 1989; 22; 15-26
Burkman LJ, Yanagimachi R, Mbizlo M; Video: Hyperactivated motility of human and hamster spermatozoa; Presented at the Annual Meeting of the American Fertility Society; 1989;
Hodgen GD, Burkman LJ, Coddington CC, Franken DR, Oehninger SC, Kruger TF, Rosenwaks Z; The hemizona assay (HZA): finding sperm that have the "right stuff".; J In Vitro Fert Embryo Transf; 1988 Dec; 5(6); 311-313
Burkman LJ, Coddington CC, Franken DR, Krugen TF, Rosenwaks Z, Hogen GD; The hemizona assay (HZA): development of a diagnostic test for the binding of human spermatozoa to the human hemizona pellucida to predict fertilization potential.; Fertil Steril; 1988 Apr; 49(4); 688-697
Burkman LJ; A microperfusion chamber for study of mammalian spermatozoa.; J Androl; 1988 Mar; 9(2); 102-108
Burkman LJ, Coddington CC; Hemi-zona assay: Is human sperm binding to the zona pellucidae predictive of in vitro fertilizing potential; Program Supplement The American College of Obstetricians and Gynecologists Annual Meeting; 1988;
Burkman LJ, Oehninger S, Johnson D, Coddington CC, Hodgen GD; Hemizona Assay (HZA) assessment of sperm (dys)function and prediction of in vitro fertilization (IVF) outcome; Program Supplement Annual Meeting of the American Fertility Society; 1988;
Burkman LJ; Surgical fertilization of hamster ova by microinjection induces the zona block to external sperm penetration; Program Supplement Annual meeting of the American Fertility Society; 1988;
Burkman LJ, Johnson D, Fulgham D, Alexander NJ, Hodgen GD; Temporal relationships between zona binding, hyperactivated motion (HA) and acrosome reactions (AR) in sperm from fertile men.; Program Supplement Serono Symposium on Gamete Physiology; 1988;
Burkman LJ, Franken d, Oehninger S, Hodgen GD; The Hemizona Assay (HZA) A predictor of human sperm fertilizing potential; Program Supplement Annual Meeting of the American Society of Andrology; 1988;
Burkman LJ, Franken D, Oehninger S, Veeck L, Hodgen G; The Hemizona Assay (HZA) the evaluation of the sperm binding potential of salt-stored human zonae pellucidae; Program Supplement Twenty-fourth Congress of the South African Society of Obstetricians and Gynaecologists; 1988;
Burkman LJ, Franken D, Oehninger S, Hodgen GD; The hemizona Assay (HZA): comparison between the binding potential of human zonae pellucida stored in DMSO versus salt solution; Program Supplement Annual Meeting of the Society for Gynecologic Investigation; 1988;
Burkman LJ, Coddington CC, Hodgen GD; Hemi-Aona pellucida for assessing human sperm function.; Program Supplement Fifth World Congress on IVF-ET; 1987;
Burkman LJ, Coddington CC, Kruger TF, Rosenwaks Z and Hodgen GD; Hemi-Zona Assay (HZA) is human sperm binding to the zona pellucida predictive of in-vitro fertilizing potential; Program Supplement Annual Meeting American Fertility Society; 1987;
Burkman LJ, Jinno M, Coddington CC; Human sperm hyperactivated motility (HA) and egg penetration.; Program Supplement Society for the Study of Reproduction; 1987;
Burkman LJ; Experimental approaches to the evaluation and enhancement of sperm function; ; 1986;
Burkman LJ, Coddington CC; Interaction of hyperactivated-like human spermatozoa with the human zona pellucida; Program Supplement American Fertility Society 42nd Annual Meeting; 1986;
Burkman LJ; Temporal pattern of hyperactivation-like motility in human spermatozoa; Program Supplement Biology of Reproduction; 1986; S1(34); 226
Van Uem JF, Acosta AA, Swanson RJ, Mayer J, Ackerman S, Burkman LJ, Veeck L, McDowell JS, Bernardus RE, Jones HW; Male factor evaluation in in vitro fertilization: Norfolk experience.; Fertil Steril; 1985 Sep; 44(3); 375-383
Burkman LJ; A mathematical analysis of sperm factors predicting IVF success; Program Supplement American Fertility Society 41st Annual Meeting; 1985;
Burkman LJ, Overstreet JW, Katz DF; A possible role for potassium and pyruvate in the modulation of sperm motility in the rabbit oviducal isthmus.; J Reprod Fertil; 1984 Jul; 71(2); 367-376
Burkman LJ; Characterization of hyperactivated motility by human spermatozoa during capacitation: comparison of fertile and oligozoospermic sperm populations.; Arch Androl; 1984 Jan; 13(2-3); 153-165
Burkman LJ, Sahaj DA; Hyperactivated motility in human fertile and subfertile sperm suspensions; Biol Reproduction; 1984; 30; 138
Burkman LJ, Syner FN, Moghissi KS, Acosta A; Sperm acrosin content and semen parameters for successful in vitro fertilization: normal and oligozoospermic groups; Fertil Steril; 1984; 41; 102S
Burkman LJ (aka: Johnson LL), Overstreet JW; Potassium and pyruvate may be regulators of rabbit oviductal sperm motility; Biol Reprod; 1982; 26; 143A
Johnson LJ, Katz, DF, Overstreet JW; The movement characteristics of rabbit spermatozoa before and after activation; Gam Research; 1981; 4; 275-282
Burkman LJ (aka) Johnson LJ, Moberg GP; Adrenocorticl response to novelty stress in rats with dentate gyrus lesions; Neuroendocrinology; 1980; 30; 187
Burkman LJ (aka Johnson) Overstreet JW, Katz DF; Motility of rabbit spermatozoa in the secretion of the oviduct; Biol Reprod; 1980; 22; 1083-1088


GRANTS

January 2006
Endocannibinoids in Newborns
Department of GYN-OB Seed Funding
Bruce Rodgers, Lani Burkman
$2,000


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