UB | MD

DESCRIPTION OF INTERESTS

My clinical and research interests center on the diagnosis and treatment of liver diseases. We are interested in the symptomatology of patients with chronic liver disease, particularly with regard to fatigue and other somatic complaints and their relationship to depression. I have participated in phase three trials of novel agents for the treatments of viral hepatitis C.

In addition, I am currently collaborating with investigators at the Research Institute on Addictions here in Buffalo. Our interests involve the epidemiology of hepatitis C in previously understudied populations. We are also interested in risk factors associated with progression of hepatitis C in those populations.

SPECIALTIES

Gastroenterology

PUBLICATIONS

Kaur N, Mahl TC; Pneumocystis jiroveci (carinii) pneumonia after infliximab therapy: a review of 84 cases.; Dig Dis Sci; 2007 Jun; 52(6); 1481-1484

Lackner JM, Lou Coad M, Mertz HR, Wack DS, Katz LA, Krasner SS, Firth R, Mahl TC, Lockwood AH; Cognitive therapy for irritable bowel syndrome is associated with reduced limbic activity, GI symptoms, and anxiety.; Behav Res Ther; 2006 May; 44(5); 621-638

Borowitz D, Goss CH, Stevens C, Hayes D, Newman L, O'Rourke A, Konstan MW, Wagener J, Moss R, Hendeles L, Orenstein D, Ahrens R, Oermann CM, Aitken ML, Mahl TC, Young KR, Dunitz J, Murray FT; Safety and preliminary clinical activity of a novel pancreatic enzyme preparation in pancreatic insufficient cystic fibrosis patients.; Pancreas; 2006 Apr; 32(3); 258-263

Kaur N., Mahl TC; Pneumocystis Jiroveci Pneumonia after Infliximab Therapy: A Review of 84 cases. (abstract); Gastroenterology; 2005; 128; A309

Kaur N, Mahl TC; Pneumocystis carinii pneumonia with oral candidiasis after infliximab therapy for Crohn's disease.; Dig Dis Sci; 2004 Sep; 49(9); 1458-1460

Lackner JM, Lockwood A., Coad M.L., Mahl TC, Firth R., Mertz H., Katz LA, Krasner S., Wack D.S., Galantowicz P.; Alterations in GI Symptoms, Psychological Status and Brain Functioning Participation in Cognitive Behavioral Therapy for IBS. (abstract); Gastroenterology; 2004; 126; A477

Lackner JM, Lockwood, A., Coad, ML., Mahl TC, Firth, R, Mertz, H., Katz LA, Krasner, S, Wack, D, Galantowicz, P; Alterations in GI symptoms, psychological status, and brain function following participation in cognitive therapy for IBS. (Poster of Distinction).; Gastroenterology; 2004; 126(S2); A 477

Lackner JM, Mahl TC, Wilding G.E.; IBS Patients’ Response to Abdominal Pain: Too Sensitive, Too Tough or Both? (abstract); Gastroenterology; 2004; 126; A481

Lackner JM, Mahl TC, Wilding, E.; IBS patients’ response to abdominal pain: Too sensitive, too tough, or both? (published abstract); Gastroenterology; 2004; 126(S2); A480

Lackner JM, Lockwood A., Mahl TC, Krasner S., Katz LA; Prospective Changes in Blood Flow, Anxiety and GI Symptoms in Irritable Bowel in Patients Treated with Cognitive Therapy. (abstract - . Presented at the 38th Annual Convention of the Association for Advancement of Behavior Therapy. November 2004. ); ; 2004;

Arif A, Levine RA, Sanderson SO, Bank L, Velu RP, Shah A, Mahl TC, Gregory DH; Regression of fibrosis in chronic hepatitis C after therapy with interferon and ribavirin.; Dig Dis Sci; 2003 Jul; 48(7); 1425-1430

Mahl TC, Ummadi S; Metronidazole and mental confusion.; J Clin Gastroenterol; 2003 Apr; 36(4); 373-374

Borowitz DS, Goss C.H., Stevens C., Hayes D., Newman L., O’Rourke A., Konstan, M., Wagener G., Moss R., Hendeles L., Orenstein D., Ahrens R., Oermann C., Aitken M., Mahl TC; Safety and Preliminary Clinical Activity of a Novel Pancreatic Enzyme Preparation, TheraClec-Total for the Treatment of Exocrine Pancreatic Insufficiency. (abstract); Pediatr Pulmonol; 2003; Sup(25); 339

Mahl TC; Approach to the patient with abnormal liver tests.; Lippincotts Prim Care Pract; 1998 Jul; 2(4); 379-389

Mahl TC; Fatigue in Patients with Chronic Hepatitis C. (abstract); Gastroenterology; 1996; 110; A1254

Mahl TC; Hetastarch Verses Albumin for Intravascular Volume Support during Large Volume Paracentesis. (abstract); Am. J. Gastro; 1995; 90; A283

Mahl TC, Shockcor W, Boyer JL; Primary biliary cirrhosis: survival of a large cohort of symptomatic and asymptomatic patients followed for 24 years.; J Hepatol; 1994 Jun; 20(6); 707-713

Critelli V.L., Lee S.J., Cohen S.A., Mahl TC; Heat Shock Protein Production from Murine Kupffer Cells. (published abstract); Gastroenterology; 1994; 106; A879

Lockwood AH, Murphy BW, Donnelly KZ, Mahl TC, Perini S; Positron-emission tomographic localization of abnormalities of brain metabolism in patients with minimal hepatic encephalopathy.; Hepatology; 1993 Nov; 18(5); 1061-1068

Mahl TC, Murphy B.W., Donnelly K.Z., Perini S., Lockwood A.H.; Functional and Cerebral Metabolic Abnormalities in Patients with Compensated Cirrhosis. (abstract); Gastroenterology; 1993; 104; A948

Tzung SP, Mahl TC, Lance P, Andersen V, Cohen SA; Interferon-alpha prevents endotoxin-induced mortality in mice.; Eur J Immunol; 1992 Dec; 22(12); 3097-3101

Mahl TC, West A.B., Kuo S., Riely C.A., Reuben A.; Methotrexate Hepatotoxicity in Psoriasis (abstract); Gastroenterology; 1992; 102; A846

Mahl TC, Tzung S-P, Lance MP, Andersen V., Cohen, S.A.; Prostaglandin E2 Inhibits Tumor Necrosis Factor Production by Kupffer Cells and Prevents Endotoxin Induced Mortality in Mice. (abstract); Gastroenterology; 1992; 102; A846

Cohen S.A., Tzung S-P, Lance MP, Andersen V., Mahl TC; Recombinant Interferon Human Rescues Mice from Endotoxemia. (abstract); Gastroenterology; 1992; 102; A794

Boyer JL, Shockcor W, Mahl TC; The natural history of primary biliary cirrhosis.; Trans Am Clin Climatol Assoc; 1992 Jan; 103; 157-163

Cohen S., Tzung S.P., Lance MP, Mahl TC; Human Recombinant Interferon Alpha Suppresses Lipopolysaccharide-Induced Tumor Necrosis Factor Production in Vivo and Decreases Mortality in Mice. (abstract); Hepatology; 1991; 14; 97A

Mahl TC, Groszmann RJ; Pathophysiology of portal hypertension and variceal bleeding.; Surg Clin North Am; 1990 Apr; 70(2); 251-266

Mahl TC, Shockcor W., Kuo S., Boyer J.L.; Primary Biliary Cirrhosis - Survival in a Cohort of 279 Patients Followed for 29 Years. (abstract); Gastroenterology; 1990; 100; A605

Mahl TC; Biochemical feminization of males with alcohol-induced liver disease.; J Gastroenterol Hepatol; 1989 Nov; 4(6); 587-589