Thomas Langan

Thomas J. Langan

Thomas J. Langan MD

UBMD Neurology


Biostatistics; Child Neurology; Developmental Neurology; Neurology; Pediatrics


Professional Summary:

My research was focused originally on using astrocyte cell cultures to shed light upon processes related to astro-gliosis, the key response of developing and mature brain to injury. The laboratory succeeded in modeling many immunochemical features of gliosis in primary brain cell culture. More recently, I have been involved in the clinical care of, and research regarding, children with leukodystrophies. This includes coordinating several clinical research projects in roles as the Director for Clinical Research for the Institute for Mylein and Glial Exploration (IMAGE) , and as the President of the New York State Krabbe Disease Consortium. Projects include expansion of the World Wide Registry for Krabbe Disease (WWR), a database that now has clinical and genetic information for over 195 affected patients afflicted with this rare disease, and examining ways to involve the WWR in national data-sharing initiatives promoted by the NIH, including the Newborn Screening Translational Research Network (NBSTRN). I have also conducted long-term follow-up studies of affected children, in conjunction with the Rare Clinical Disease Research Network (RDCRN), am examining neuro-developmental parameters before and after therapeutic transplantation. With collaborators, I am participating in research to uncover new biomarkers for newborn screening of neurodegnerative disorders, and to develop novel therapies for these diseases. I am also the Director of the Headache and Concussion clinics at Children’s Hospital of Buffalo. These clinical leadership roles in Western New York, New York State and the United States can facilitate significant recruitment into multi-center research studies.


Biostatistics, Child Neurology, Developmental Neurology, Neurology, Pediatrics

Physician Gender:


Hospital Locations (for inpatients only):

  • UBMD Neurology at Conventus

Education and Training:

  • Neuro-Chemistry, Washington University (1986)
  • Residency, Neurology, Washington University (1984)
  • Residency, Pediatrics, Washington University (1981)
  • MD, Medicine, Brown University (1979)
  • Biology, Brown University (1976)

Awards and Honors:

  • Castle Conolly Best Doctor (2015)
  • Data Safety and Monitoring Board (2015)
  • President of Medical Advisory Committee (2014)
  • Examiner, American Board of Psychiatry and Neurology (2013)
  • Secretary of Governing Board of Faculty Practice Management Plan (2009)
  • President of Governing Board of Faculty Practice Management Plan (2005)
  • Nominated as Counselor for the East, Child Neurology Society (2001)
  • Elected to Best Doctors in America (1999)
  • Director, Division of Child Neurology, Neurologist-in-Chief, Children’s Hospital of Buffalo (1998)
  • Elected chairperson of the Interdepartmental Graduate Group in Neuroscience, SUNY at Buffalo (1997)
  • Symposium Organizer, 1997 Meeting of Child Neurology Society. “Neuronal-Glial Interaction." (1997)
  • Symposium Organizer, 1996 Meeting of Child Neurology Society. “Advances in Developmental Neurology” (1996)
  • Symposium Organizer, 1996 Meeting of Child Neurology Society. “In vivo Assessment of Cognition and Learning.” (1996)
  • Appointed Chairperson of Scientific Selection Committee, Child Neurology Society (1995)
  • Appointed Organizer, Cellular Neuroscience Research Group, School of Medicine and Biomedical Sciences (1994)
  • Appointed to Scientific Selection Committee for the National Meeting of the Child Neurology Society (1994)
  • Elected to regular membership, American Society for Neurochemistry (1993)
  • Elected chairperson, Committee for Biomedical Research, Faculty Council, SUNY at Buffalo (1992)
  • Ad hoc reviewer, Journal of Cellular Physiology (1992)
  • Named to Steering Committee, Center for Molecular and Cellular Neuroscience, SUNY at Buffalo (1991)
  • Nominee- Junior investigatorship of Howard Hughes Medical Institute. One of two nominees from School of Medicine (1990)
  • Nominee- Sinsenheimer Research Award. Single nominee of School of Medicine (1988)
  • Honorable Mention - S. Weir Mitchell Competition (1986)

Research Profile:

This UBMD physician is also a member of the Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo, teaching the next generation of doctors and researching to advance care in WNY and beyond. Learn more about this physician's research and teaching activities, as well as view credentials, publications, professional involvement and more below.

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