Clare Twist

Clare J. Twist

Clare J. Twist MD, MS

UBMD Pediatrics


Pediatric Hematology-Oncology; Pediatrics

Accepting new patients

Professional Summary:

I joined the faculty of the Jacobs School of Medicine and Biomedical Sciences in 2016 as Professor of Oncology and Director of Pediatric Developmental Therapeutics at the Roswell Park Comprehensive Cancer Center. I am a board-certified pediatric hematologist/oncologist and clinical investigator. My area of clinical expertise focuses on solid tumor malignancies in children and young adults. My research interests have been driven by the clinical challenges in high risk pediatric malignancies. A major focus of my clinical investigation effort over the past 15 years has been in the design of clinical trials through the Children’s Oncology Group (COG) for patients with neuroblastoma. I have served since 2006 on the COG Neuroblastoma Steering Committee, helping to define and prioritize research objectives for this disease. I served as study chair of the COG Phase III study ANBL0531 for patients with Intermediate Risk Neuroblastoma, which defined a practice-changing new standard of care therapy for patients with non-high risk neuroblastoma in North America.

Since joining the faculty in the Cancer and Blood Disorders Program at Roswell Park and Oishei Children’s Hospital in 2016, I have overseen the clinical trials program for pediatric oncology and serve as the institutional principal investigator for COG. In my role as Director of Pediatric Developmental Therapeutics at Roswell Park, I am building a program to support the development and implementation of early phase trials and novel therapies for children and young adults with high risk malignancies.

I serve as the Program Director of the Pediatric Hematology/Oncology Fellowship Training Program at the Jacobs School and Roswell Park/Oishei Children’s Hospital. On a national level, I have served on the Education Committee of the American Society of Clinical Oncology (ASCO), the Training Committee and the Certification and Continuing Education Committee of the American Society of Pediatric Hematology/Oncology (ASPHO) and the National Heart, Lung, and Blood Institute (NHLBI) Taskforce on the Future of the Workforce in Hematology, as well as serving on the American Board of Pediatrics subboard in Hematology/Oncology since 2008.


Pediatric Hematology-Oncology, Pediatrics

Patients Treated:

Children, Adolescents

Physician Gender:



UBMD at Roswell Park Comprehensive Cancer Center
Katherine, Anne and Donna Gioia Pediatric Hematology Oncology Center
Roswell Park Comprehensive Cancer Center
Elm and Carlton Streets
Ground Floor
Buffalo, New York 14263
Phone: (716) 845-4447
Fax: (716) 845-3588
Accepting new patients

Insurance Accepted:
  • Aetna U.S. Healthcare
  • Blue Cross & Blue Shield of WNY Inc
  • CIGNA HealthCare
  • Community Blue (HMO)
  • Community Blue Advantage
  • Coventry
  • Empire
  • Fidelis
  • Independent Health Association (HMO)
  • Independent Health Medisource
  • Lifetime Benefit Solutions / RMSCO
  • MVP Healthcare
  • Magnacare
  • Medicaid
  • Medicare
  • Nofault
  • North American Administrators
  • Nova
  • Preferred Care
  • Railroad Medicare
  • TriCare/Champus
  • Tricare
  • United Healthcare
  • Univera Health Care (HMO)
  • Veterans Administration
  • WellCare
  • Workers Comp

Board Certifications:

  • Board Certification, American Board of Pediatrics
  • Board Certification, American Board of Pediatrics, Sub-board in Pediatric Hematology/Oncology

Education and Training:

  • Fellowship, Pediatric Hematology/Oncology, Harvard Medical School (1993)
  • Fellowship, Pediatric Hematology/Oncology, Harvard Medical School (1991)
  • Residency, Pediatrics, Northwestern University (1990)
  • Internship, Pediatrics, Northwestern University (1988)
  • MD, Medicine, Albany Medical College (1987)
  • MS, Natural Sciences/Immunology, University at Buffalo/Roswell Park Memorial Institute (1984)
  • BS, University of Notre Dame (1982)

Awards and Honors:

  • Children's Memorial Hospital: Outstanding Resident Teaching Award (1990)
  • Albany Medical College: Lamb Foundation Prize (1987)
  • Albany Medical College: Senior Medical Student Special Award (1987)
  • Buffalo Spree Magazine: Top Doctors in Western New York (2019-2021)

Research Profile:

This UBMD physician is also a member of the Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo, teaching the next generation of doctors and researching to advance care in WNY and beyond. Learn more about this physician's research and teaching activities, as well as view credentials, publications, professional involvement and more below.

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