Jonathan Riley

Jonathan Riley

Jonathan Riley MD

UBMD Neurosurgery


Neurological Surgery

Accepting new patients

Professional Summary:

Dr. Riley is an Assistant Professor of Neurosurgery at the State University of New York (SUNY) at Buffalo, having joined in Fall 2017. Dr. Riley is the Medical Director of Functional Neurosurgery and Fellowship Director for the Stereotactic & Functional Neurosurgery fellowship position. After receiving a Bachelors of Science in Engineering from Mercer University in 2000, Dr. Riley completed medical school at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University (2009), simultaneously obtaining a Masters of Science in Pathology. He went on to complete his neurosurgical residency at Emory University (2016).

During his neurosurgical residency, he completed an enfolded Stereotactic and Functional Neurosurgery Fellowship and completed a post-residency Fellowship position in the same at Thomas Jefferson University Hospital.

Dr. Riley placed emphasis on this subspecialized training to be best positioned to provide a full range of surgical treatment options to patients with afflictions affecting the function of the central nervous system. These include surgical treatments for the broad spectrum of Movement Disorders, epilepsies, pain syndromes, and emerging psychiatric indications.

Throughout medical school and residency, Dr. Riley has meaningfully and longitudinally participated in translational and clinical research agendas. These have included both small and large animal work and have focused on the clinical translation of biologics-based therapeutics with an emphasis on development of approaches to therapeutics delivery to the central nervous system. This has provided a background in all aspects of translation from large animal work through clinical trial completion. Active research interests include the use of small animal epilepsy models to develop and optimize neuromodulation-based candidate therapies for the treatment of medically refractory epilepsy.

Dr. Riley’s additional professional interests include international neurosurgical outreach and program development. .


Neurological Surgery

Patients Treated:

Adults, Seniors/Elderly

Physician Gender:



UBMD Neurosurgery
Neurosurgery Clinic Location

Office Hours: Thursday 0845-330pm
Accepting new patients

Orchard Park Office Location
5959 Big Tree Road
Ste 103
Orchard Park, New York 14227
Accepting new patients

Hospital Locations (for inpatients only):


Education and Training:

  • Fellowship, Stereotactic and Functional Neurosurgery, Thomas Jefferson University (2017)
  • Fellowship, Stereotactic and Functional Neurosurgery, Emory University (2016)
  • Residency, Neurological Surgery, Emory University (2016)
  • MD, Medical Degree, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University (2009)
  • MS, Pathology, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University (2009)
  • BS, Engineering, Mercer University, Magna Cum Laude (2004)

Innovations and Patents:

  • Spinal Frame for Resource Limited Setting

Research Profile:

This UBMD physician is also a member of the Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo, teaching the next generation of doctors and researching to advance care in WNY and beyond. Learn more about this physician's research and teaching activities, as well as view credentials, publications, professional involvement and more below.

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