Weidun Alan Guo

Weidun Alan Guo

Weidun Alan Guo MD, PhD, FACS

UBMD Surgery


Professional Summary:

I am an acute care surgeon board-certified in both surgery and surgical critical care, with clinical focus in trauma, emergency general surgery and surgical critical care. The most important part of my job is providing compassionate surgical care to my patients, who are often acutely injured and/or critically ill. I have a deep awareness of, and empathy for my patients’ suffering, and I do my best to alleviate it. I practice medicine with the golden rule — “Do unto others as you would have them do unto you”. I believe that an optimal medical decision is the one that integrates information about the patient’s clinical state and circumstances, the available research evidence, as well as the patient’s values and preferences. I also perform laparoscopic surgery, gastrointestinal surgery (small bowel, colorectal and biliary), complex hernia repair, endoscopy and provide wound care.

My scholarly focus is in the area of trauma and critical care-related pathophysiology. In basic science, I was the first to demonstrate that food high in advanced glycation end-products (AGE) and its interaction with the receptor (RAGE) predispose patients for aspiration-induced acute respiratory distress syndrome (ARDS) in trauma. In clinical research, I have been pursuing interests in areas of utilization of imaging study in trauma, prevention of blood clot formation in head injury patients, ICU quality improvement. I was a co-investigator on NIH-funded grants for evaluation of aspiration biomarkers in trauma and surgery, as well as on an Surgical Infection Society multicenter study on duration of antibiotics for abdominal infection. I have mentored numerous surgical residents and medical students in research, which has led to them receiving national research awards. I have a bibliography of 60 peer-reviewed scientific publications and 6 book chapters, in addition to many oral and poster presentations. I am an associate editor for the Journal of Surgical Research, and an member of editorial board for many leading surgical journals.

I have a passion for teaching medical students and residents. I find satisfaction in sharing my knowledge, experience and wisdom with those in the training phase of their careers. The trainees’ inquiries have helped me stay current in the field, and ultimately help me render the best care to my patients. As a surgeon, role model and mentor, I have inspired many medical students to pursue surgery as a career.

Physician Gender:



UBMD Surgery
Erie County Medical Center
Department of Surgery
462 Grider Street
DK Miller Building, Third Floor
Buffalo, New York 14215
Office Hours: 8:30-4:30
Phone: (716) 898-5186
Fax: (716) 898-3194
Contact: Rosemary Boerschig

Insurance Accepted:
  • Aetna U.S. Healthcare
  • Blue Cross & Blue Shield of WNY Inc
  • CIGNA HealthCare
  • Community Blue (HMO)
  • Community Blue Advantage
  • Empire
  • Fidelis
  • GHI
  • Independent Health Association (HMO)
  • Magnacare
  • Medicaid
  • Medicare
  • NYS Medicaid
  • Nofault
  • North American Administrators
  • Nova
  • Preferred Care
  • Railroad Medicare
  • TriCare/Champus
  • Tricare
  • United Healthcare
  • Univera Health Care (HMO)
  • Veterans Administration
  • Workers Comp

Hospital Locations (for inpatients only):

  • Kaleida Health - Millard Fillmore Suburban

Education and Training:

  • Other, Surgeons as Leaders: From Operating Room to Boardroom, Division of Education, The American College of Surgeons (2014)
  • Other, SUS Mid-Career Academic Surgery Professional Development Course (2013)
  • Residency, General Surgery Residency, The Cleveland Clinic Heath System, Huron Hospital (2006)
  • Fellowship, Clinical Fellowship, Trauma and Surgical Critical Care., The Ohio State University (2004)
  • Residency, General Surgery Residency, UMDNJ-New Jersey Medical School (2003)
  • Fellowship, Laparoscopic Research Fellowship, University of Texas Southwestern Medical Center, Department of Surgery (1999)
  • Fellowship, Post-Doctoral Research Fellowship, Dept. of Surgery, UMDNJ-New Jersey Medical School (1997)
  • Fellowship, Post-doctoral Research Fellowship, Dept. of Surgery, Louisiana State University Medical Center (1994)
  • PhD, Lund University, Sweden (1993)
  • Residency, General Surgery Residency, Nanking Railway Medical School, Guangzhou Central Hospital (1990)
  • MD, Shantou University Medical College, China (1984)

Awards and Honors:

  • 1. Honoree, The Gold Humanism Honor Society (GHHS) (2018)
  • 2. Royal Australasian College of Surgeons/AAS International Visiting Professorship Award (2016)
  • 3. Faculty Teaching Award, University at Buffalo (2011)
  • Young Scientists Award (1993)
  • The Lars Hierta Memorial Foundation Award (1992)
  • Medical Faculty (School) Scholarship (1992)
  • National Medical School Residents Award (1987)
  • Medical School Scholarship (1984)

Research Profile:

This UBMD physician is also a member of the Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo, teaching the next generation of doctors and researching to advance care in WNY and beyond. Learn more about this physician's research and teaching activities, as well as view credentials, publications, professional involvement and more below.

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